10h a.m.

Travel to Plovdiv   - accommodation in Novotel Plovdiv

13.00 – 14.30

Lunch

14.45 - 16.00

Chairman: Olivier Mozziconacci

14.45-15.30

Jean Cadet, Thierry Douki, Noureddine Belmadoui, Didier Gasparutto and Jean-Luc Ravanat – Damage to DNA induced by oxidative processes: recent aspects and perspectives

15.30-16.00

Panagiotis Kaloudis - Chemical Radiation Studies of 8-Bromo-2-aminoadenosine in Aqueous Solutions

16.00 – 16.30

Coffee break

16.30 - 17.30

Chairman:  Noureddine Belmadoui

16.30-17.00

Fabien Boussicault -  Influence of oxygen concentration on the behavior of 2’-deoxyadenosine and 2’-deoxyinosine

17.00-17.30

Cecilia Paris - Photoinduced sensitization processes of C5’ ketoprofen-purine nucleosides as models for oxidative DNA damage

20.00

Dinner

9.00 – 10.30

Chairman:  Herve Menoni

9.00-9.30

Noureddine Belmadoui, Peggy Regulus, Jean-Luc Ravanat, Didier Gasparutto, Jean Cadet – Radiation – induced clustered DNA damage, synthesis of photolabile precursors

9.30-10.00

Sophie Mourgues, Martine E. Lomax, Peter O’Neill - Base excision repair processing of an abasic site/single strand break lesions within clustered damage site associated with XRCC1 deficiency

10.00-10.30

laura Eccles, Martine Lomax, Peter O’Neill – Repair of clustered DNA damage: Processing of three – lesion clusters

10.30 – 11.00

Coffee break

11.00-12.00

Chairman:  Cecilia Paris

11.00-11.30

Dimitris Stathis and Thanasis Gimisis - Structure determination of DNA base lesions through oxidation of gluconucleosides and synthesis, coupled with protein crystallography

11.30-12.00

Olivier Mozziconacci – The methanesulfonyl radical a model of the thiy1 radical in oxygenated media. Its role in the Cis – Trans isomerization of the monounsaturated fatty acids

12.30 – 13.30

Lunch  

14.00 – 15.30

Chairman: Sophie Mourgues

14.00-14.30

Hervé Menoni, Philippe Bouvet, Dimitar Angelov - BER of single and clustered oxidative lesions within in vitro reconstituted nucleosomal templates

14.30-15.00

Nataliya Kitsera, Andriy Khobta, Bernd Epe – A strategy for generation of covalently-closed plasmid DNA with specifically incorporated tandem lesions

15.00-15.30

Andriy Khobta, Nataliya Kitsera, Bernd Epe – Transcription and chromatin modifications at the oxidatively damaged gene

15.30 – 16.00

Coffee break

16.00-17.00

Chairman: Nataliya Kitsera

16.00-16.30

Aaron Alt ? - .....................................................................

16.30-17.00

Heiko Müller ?- ............................................................................... 

17.00 – 18.00

Business meeting

20.00

Dinner