Monday 22 nd May 2006
Late pm Arrival of delegates
19.30 Dinner (to be served in the restaurant)
Tuesday 23 rd May 2006
7.30-9.00 Breakfast
09.00-09.15 Welcome and Introduction by Sergio di Virgilio (EU), (Scientific Officer)
09.15-10.00 Project Overview, Peter O'Neill, (MRC), (Co-ordinator of CLUSTOXDNA)
10.00-11.00 I: Detailed Review by Partners – Chair: Herve Menoni
Sophie Bellon, MRC , UK – Mutagenic potential of thymine glycol within clustered DNA Damage
Boleslaw Karwowski, CEA, France – The 5',8-cyclo-2'-eoxyadenosine tandem lesion: from quantum chemistry studies to the delineation of biological end points
11.00-11.30 Coffee break
11.30-13.00 II: Detailed Review by Partners – Chair: Jerome Trzcionka
Antonio Manetto, LMU Munich , Germany - Excess Electron Transfer Through DNA Investigated with Differently Strong Electron Acceptors Reveals Complex Sequence Dependence 3
Aaron Alt, LMU Munich , Germany - Low fidelity DNA polymerase in ternary complexes with lesion containing DNA
Panagiotis Kaloudis, CNR-ISOF , Italy – One-electron reduction of 8-bromopurine nucleosides
13.00-14.15 Lunch
14.15-15.30 III: Detailed Review by Partners – Chair: Sophie Mourgues
Herve Menoni, ISSP-BAS , Bulgaria – The effect of ATP dependent chromatin remodelling complex on Base Excision of 8oxoG within positioned canonical or variant (H2A.Bbd) nucleosomes
Andriy Khobta, UNIMAINZ, Germany – Inactivation of a reporter gene by oxidative stress and by 8-oxoguanine in the transcribed DNA
15.30-16.00 Afternoon Tea
16.00-17.30 IV: Detailed Review by Partners – Chair: Panagiotis Kaloudis
Cecilia Paris, UPVLC, Spain – Laser Flash Photolysis and Photochemical Experiments on Nucleoside Derivatives, Model Dyads for Oxidative DNA Damage Studies
Jerome Trzcionka, UPVLC, Spain – Model DNA photolesions: photosensitized formation and repair by carprofen derivatives
Thanasis Gimisis, NKUA, Greece - Synthesis, Generation and Structure Determination of DNA Base Oxidation Products
19.30 Dinner (private dinner to be served in the meeting room)
Wednesday 24 th May 2006
7.30-9.00 Breakfast
9.00-10.00 Business Meeting of PI's (in coffee area)
9.00-10.00 Meeting of Scientific Officer (Sergio di Virgilio) with Researchers
10.00-11.00 Coffee break (for Researchers)
10.00-11.00 Meeting of Scientific Officer (Sergio di Virgilio) with PI's
11.00-12.00 Concluding session (Scientific Officer, ERs/ESRs and PI's)
12.00 Lunch
pm Meeting finishes |